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Macrophage polarization comes of age

by Stefania Parodi last modified 2009-11-23 11:26

Mantovani A, Sica A, Locati M. Macrophage polarization comes of age. Immunità. 2005. 23: 344 - 346

Functional polarization of macrophages into M1 or M2 cells is an operationally useful, simplified conceptual framework describing the plasticity of mononuclear phagocytes. Genetic approaches have begun to shed new light on mechanisms underlying macrophage polarization and on the actual in vivo significance of polarized M2 cells.

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