Genomic DNAcopy number aberrations are frequent in solid tumours although their underlying causes of chromosomal instability in tumours remain obscure. In this paper we show how Artificial Immune System (AIS) paradigm can be successfully employed in the elucidation of biological dynamics of cancerous processes using a novel fuzzy rule induction system for data mining (IFRAIS) 1 of aCGH data. Competitive results have been obtained using IFRAIS. A biological interpretation of the results carried out using Gene Ontology is currently under investigation.